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Biology Refresher: Cell Division

Sister Chromatids

Sister Chromatids: Two identical copies of the same chromosome formed by DNA replication, attached to each other by a structure called the centromere. During cell division, they are separated from each other, and each daughter cell receives one copy of the chromosome. 

Diploid vs. Haploid

Mitosis vs. Meiosis

Mitosis

Meiosis

Cells undergo one round of division

Cells undergo two rounds of division

Creates all body (somatic) cells

Creates only sex cells

gametes: egg and sperm

Produces two daughter cells

Produces four daughter cells

Daughter cells are diploid (2n) – contain a full set of DNA

Daughter cells are haploid (n) – contain only half a set of DNA

Daughter cells are genetically identical

Daughter cells are genetically different

Plays a role in growth and repair

Plays a role in sexual reproduction
*fertilization occurs when the haploid egg and sperm unit to form a zygote

Mutations and Cancer

Cancer: A collective name for many different diseases caused by a common mechanism, uncontrolled cell division.

What causes cancer? A mutation, an error in DNA replication during the S phase of interphase. All cancers begin when a gene mutation gives rise to a faulty protein that participates in the process of cell reproduction. Cell division can then occur uncontrolled.

The Stages of Mitosis

Stages of Mitosis

Events that Occur

Interphase

  • G1 – cell growth
  • S – DNA replication
  • G2 – cell growth

Prophase

  • Nuclear membrane breaks down
  • Spindle of microtubules forms
  • DNA condenses into chromosomes

Metaphase

  • Spindle that is attached to the centromere of sister chromatids pulls them to the cell center

Anaphase

  • Spindle is depolymerized, pulling sister chromatids apart at their centromere

Telophase

  • Nuclear membrane reforms
  • Spindle is disassembled
  • Chromosomes decondense

Cytokinesis

  • Cleavage furrow in animal cells, cell plate in plant cells, pinches the cytoplasm into two. Two daughter cells result

Visual of the Stages of Mitosis

Video Review: The Stages of Mitosis

Video Review: Mitosis vs. Meiosis

Binary Fission

Binary fission: The process through which asexual reproduction happens in bacteria. During binary fission, a single organism divides to become two independent organisms. 

As this process is asexual, not involving the fusion of male and female gametes, there is not increased genetic diversity in the offspring. 

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